Denver Health COMBAT Research Study

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Who Qualifies for the COMBAT Study?

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What is the current standard of care?  How are trauma patients usually treated?

Based on the Advanced Trauma Life Support Guidelines from the American College of Surgeons, the current standard of care for trauma patients is to give sterile saline (salt water) through the veins either at the scene or in the ambulance.  When the patients arrive at the hospital, they are evaluated and are given blood products including red blood cell and plasma transfusions, if they are bleeding.

How is the control and experimental group different? 

Trauma patients in hemorrhagic shock are likely to receive AB-FP24 plasma regardless of the group assigned.  The experimental group would receive the AB-FP24 plasma sooner (at the start of the resuscitation period) than the control group (who gets it after the initial evaluation).

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